Abstract:

Objective

To investigate the clinical classification of the lactational mastitis and the strategies of individualized therapy.

Methods

We retrospectively analyzed 1650 patients with lactational mastitis admitted in our hospital from July 2006 to August 2011. They were divided into two groups for comparison: the conventional therapy group (n=736) and the individualized therapy group (n=914). The numeration data were analyzed using chi-square test,measurement data using two-sanple t test.

Results

In the individualized therapy group, the cure rate was 92.8%(849/914), the average time of symptom relief (1.86±1.97) d, milk regurgitation rate 13.3%(122/914), the rate of abscess formation (7.2%,65/914), and the recurrence rate(6.1%,56/914), which were significantly lower than those in the conventional therapy group(P＜0.01). In the conventional therapy group, the rate of abscess formation(13.8%,59/427)and milk regurgitation rate (42.4%,181/427)in peripheral mastitis patients were significantly lower than those in the patients with central mastitis (51.0%,26/51;84.3%,43/51; P＜0.05). In the individualized therapy group,the rate of abscess formation(5.9%,30/505)and milk regurgitation rate (4.2%,21/505) in peripheral mastitis patients were significantly lower than those in the patients with central mastitis (25.9%,15/58;70.7%,41/58; P＜0.05).

Conclusion

Based on the clinical classification, the individualized therapy should be given to lactational mastitis patients, which can improve the cure rate, reduce the milk regurgitation,recurrence and abscess formation.

Key words: Mastitis, Lactation, Clinical classification, Individualized therapy strategy